Urolithin A has been shown to have potent anti-inflammatory properties. Chronic inflammation is known to be associated with many chronic diseases such as cancer, Alzheimer’s disease, and cardiovascular disease. Urolithin A can reduce the production of pro-inflammatory cytokines and enzymes, thereby reducing inflammation in the body.
Studies have shown that Urolithin A can induce apoptosis (programmed cell death) in cancer cells. It has also been found to inhibit the growth of cancer cells, particularly in prostate cancer and breast cancer. Additionally, Urolithin A has been shown to have chemopreventive properties, which means it can prevent the development of cancer.
Urolithin A has been shown to have anti-aging properties. In a study conducted on nematodes (worms), Urolithin A was found to extend their lifespan by up to 45%. The mechanism behind this is that Urolithin A activates a cellular process called mitophagy, which helps to remove damaged mitochondria from the cell. Mitochondria are the powerhouses of the cell and are responsible for producing energy. As we age, the mitochondria become damaged, which can lead to a range of age-related diseases. By activating mitophagy, Urolithin A helps to remove these damaged mitochondria, thereby reducing the risk of age-related diseases.
Urolithin A has been found to have positive effects on muscle health. In a study conducted on mice, Urolithin A was found to increase muscle mass and endurance. It does this by activating a cellular pathway called the PGC-1α pathway, which is involved in muscle growth and endurance.
Urolithin A has been found to have neuroprotective properties. It has been shown to protect neurons from oxidative stress, which can lead to neurodegenerative diseases such as Alzheimer’s disease and Parkinson’s disease. Additionally, Urolithin A has been found to improve cognitive function in mice.