What Is GlyNAC?
GlyNAC is a powerful combination of the amino acids glycine and N-acetylcysteine (NAC) that works synergistically to boost your body’s production of glutathione, the “master antioxidant” that protects cells from oxidative damage. Research shows GlyNAC helps correct age-related declines in cellular defenses and supports healthier aging. The Aeternum Company+1
Why GlyNAC Matters for Aging & Longevity
As we age, levels of glutathione, a key molecule that neutralizes free radicals and protects mitochondria naturally decline. This leads to increased oxidative stress, mitochondrial dysfunction, inflammation, and other hallmarks of aging. Supplementing GlyNAC helps restore glutathione levels, which in turn may improve:
- Antioxidant defense and cellular protection
- Mitochondrial energy production
- Inflammation regulation
- Insulin sensitivity and metabolic health
- Muscle strength and physical performance
- Cognitive function and mental clarity PubMed+1
Scientific Evidence & Clinical Insights
Preclinical studies in mice show that GlyNAC supplementation can extend lifespan and improve age-related cellular defects, including oxidative stress and mitochondrial dysfunction. In one study, mice given GlyNAC lived about 24% longer than controls, with better cellular health markers. PubMed
In human clinical trials, older adults taking GlyNAC for several weeks experienced significant improvements in glutathione levels, mitochondrial function, inflammation, insulin resistance, muscle strength, gait speed, and cognitive performance compared to placebo. PubMed
Practical Benefits Covered in Episode 2
✔ Enhances antioxidant defenses by restoring glutathione
✔ Supports healthier mitochondria and cellular energy
✔ Improves strength, endurance, and physical function
✔ Boosts brain health and cognitive performance
✔ Helps counter key biological drivers of aging Baylor College of Medicine
Who Can Benefit from GlyNAC
While aging adults see the most dramatic clinical benefits, GlyNAC may also support:
- People with elevated oxidative stress
- Anyone seeking stronger antioxidant defenses
- Individuals focused on metabolic and mitochondrial health
- Longevity enthusiasts aiming to optimize cellular function
As with all supplements, individuals should consult a healthcare professional before beginning long-term use.
Related Episodes & Longevity Resources
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Episode 9: Coffee & Longevity
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Episode 12: Longevity Genes